You need to enable JavaScript to use the communication tool powered by OpenWidget

GLP-1 Weight Optimization in Los Angeles

GLP-1 medications like semaglutide (like Ozempic®, Wegovy®, and Rybelsus®) and tirzepatide like Zepbound® or Mounjaro®) have been shown to have many positive effects, including and especially weight loss.

Semaglutide & Tirzepatide for Sustainable Weight Loss and Inflammation Mediation

Golden Afternoon Clinic offers physician-supervised GLP-1 weight optimization therapy using high-quality compounded semaglutide and tirzepatide. These medications support healthy, gradual weight loss by improving metabolic function, reducing appetite, and stabilizing blood sugar, helping patients achieve results that feel natural, steady, and sustainable.

Our program is designed to be affordable, supportive, and grounded in clinical safety. Our processes ensure personalized dosing and a compassionate care experience.

What Are GLP-1 Medications?

GLP-1 medications like semaglutide and tirzepatide work by mimicking a naturally occurring hormone that helps regulate:

  • Appetite
  • Blood sugar levels
  • Digestion
  • Insulin response
  • Satiety cues

These medications help patients feel fuller longer, reduce cravings, and support metabolic balance—making weight loss more achievable without extreme dieting.

Why We Offer Compounded Semaglutide & Tirzepatide

When clinically appropriate, we can discuss FDA-approved GLP-1 medications and, when necessary and permitted, compounded formulations prepared by licensed U.S. pharmacies. The decision is individualized (e.g., tolerability, dosing needs, access considerations), and we review benefits, risks, and alternatives during your medical visit.

We work with licensed U.S. pharmacies and require appropriate documentation of sourcing and quality controls.

Free consultation

How GLP-1s Support Weight Loss

GLP-1 medications work through several synergistic pathways:

• Appetite suppression

Reduced hunger and fewer cravings make portion control feel effortless.

• Slower gastric emptying

Food stays in your stomach longer, prolonging fullness and reducing spikes in blood sugar.

• Improved metabolic efficiency

Better glucose regulation can support healthier energy levels and reduced fat storage.

• Reduced reward-driven eating

Many patients report decreased emotional or stress-related eating.

• Steady weight loss

Most patients see gradual, natural-feeling changes over weeks to months.

Free consultation

Our GLP-1 Program Includes:

  • Personalized dosing plan based on your health profile
  • Compounded semaglutide or tirzepatide at an accessible price
  • Gradual titration for comfort and safety
  • Monitoring & support through regular check-ins
  • Guidance on nutrition and lifestyle optimizations
  • Option to combine with mood or wellness therapies for whole-person support

Compounded medication notice: Our program includes compounded semaglutide or tirzepatide prepared by a licensed compounding pharmacy. Compounded drugs are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality. Compounded formulations may be considered only when clinically appropriate and legally permitted based on an individualized medical evaluation.

These medications are prescribed as part of a clinician-supervised plan. Outcomes vary by individual, and no specific results are guaranteed.

-------------------------------------------------------------------------------------------

Benefits of GLP-1 Therapy at Golden Afternoon

Affordable access

Compounded formulas offer a cost-effective and reliable supply.

Supportive, nonjudgmental environment

Weight journeys can be emotional, our approach is respectful, compassionate, and realistic.

Steady, sustainable results

No crash dieting or extreme restrictions.

Convenient Santa Monica location

Easy access for Westside residents and surrounding LA neighborhoods.

Get started

Ketamine and GLP-1 Together

A Supportive, Whole-Person Approach to Weight and Mental Health

At Golden Afternoon, we understand that weight, mood, and motivation are often deeply connected. Many people struggle not because they lack willpower, but because biology and mental health are working against them at the same time. Our care model is designed to address both—thoughtfully, safely, and with close medical support.

1) What GLP-1 medications do

GLP-1 medications work on gut–brain signaling pathways that help regulate appetite and fullness. For many patients, this can mean:

  • Reduced hunger and cravings
  • Less “food noise” or constant preoccupation with eating
  • Greater ability to follow nutrition and lifestyle recommendations

GLP-1 therapy supports the metabolic side of weight management, helping the body respond more appropriately to food intake rather than relying on constant effort or restriction alone.

2) How ketamine therapy works

Ketamine therapy is used in carefully selected patients to support mental health, particularly symptoms of depression. Unlike traditional antidepressants, ketamine works through pathways involved in neuroplasticity—the brain’s ability to form new connections.

Clinically, patients may experience:

  • Improvement in mood or outlook
  • Reduced emotional “stuckness”
  • Greater flexibility in thought patterns and motivation

This can be especially meaningful for individuals whose mood symptoms interfere with self-care, consistency, or follow-through.

3) Why combining them can be helpful

While these treatments work in different ways, they may be complementary when used thoughtfully:

  • GLP-1 medications can make physical changes feel more achievable by reducing appetite-driven resistance.
  • Ketamine therapy can reduce psychological barriers such as low motivation, hopelessness, or emotional eating.
  • Together, they may help patients engage more fully in lifestyle changes, follow-up care, and long-term health goals.

Importantly, this is not about “more medication.” It is about coordinated, individualized care that addresses both body and mind.

Our clinic philosophy

We provide this care in a calm, supportive environment where patients are treated with time, attention, and respect. Our staff is warm, highly trained, and attentive—focused on helping patients feel safe, informed, and genuinely cared for at every visit. We believe outcomes are better when patients feel supported, not rushed or judged.

Important information and disclaimer

The information on this page is for educational purposes only and does not constitute medical advice. All treatments require an individualized medical evaluation.

If compounded medications are prescribed, please note that compounded drugs are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality in the same way as FDA-approved products. The FDA has issued safety communications regarding some compounded GLP-1 products, including concerns about dosing errors and the use of ingredient forms that differ from those in FDA-approved medications. Patients are encouraged to discuss risks, benefits, and alternatives in detail with their clinician.

You’ve got questions, we’ve got answers.

Still have questions about GLP-1, ketamine and Golden Afternoon's approach to both? These are common questions we have heard asked.
Do I have to do both treatments?

No. Some patients benefit from one modality alone, while others may benefit from a combined approach. Recommendations are always individualized based on your medical history, goals, and preferences. Our role is to help you understand your options—not to push a one-size-fits-all plan.

Is this approach safe?

Safety is central to our care model. All patients undergo medical screening before starting treatment, and we monitor response and side effects closely throughout care. Mental health symptoms are assessed and followed as appropriate, and we coordinate with outside clinicians when needed.

Will this guarantee weight loss or mood improvement?

No treatment can guarantee specific outcomes. Weight and mental health are complex and influenced by many factors. Our approach is designed to support metabolic and psychological health, but individual responses vary.

Can GLP-1 medications affect mood?

Large clinical trials of GLP-1 medications for obesity have not shown an increased risk of depression or suicidal behavior compared with placebo. That said, mental health is always monitored as part of responsible care, particularly in patients with a history of mood disorders.

How quickly does ketamine therapy work?

Some patients notice changes in mood within days, while others experience more gradual improvement over time. Ketamine therapy is not a cure and works best as part of a broader treatment plan that may include psychotherapy, lifestyle support, and ongoing medical care.

What if I’ve struggled with weight for years?

Many patients come to us after repeated attempts that felt frustrating or discouraging. We view this not as a failure of effort, but as a sign that biology and mental health may need to be addressed together. Our goal is to meet you where you are and move forward at a sustainable pace.

What makes your clinic different?

We intentionally provide care in a calm, unrushed environment. Our staff is experienced, attentive, and deeply invested in patient well-being. We believe feeling safe, supported, and respected is an essential part of healing—and we design our clinic experience accordingly.

Are compounded medications FDA-approved?

No. Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality in the same way as FDA-approved drugs. When compounded medications are used, we discuss this openly and review potential risks, benefits, and alternatives so patients can make informed decisions.