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IV Ketamine Infusion Therapy in Los Angeles

IV ketamine infusion therapy is one of the most effective and fast-acting treatments for treatment-resistant depression, anxiety disorders, PTSD, OCD, and certain forms of chronic pain.

A Rapid-Acting Treatment for Depression, Anxiety, PTSD & Chronic Pain

At Golden Afternoon Clinic in Santa Monica, all ketamine infusions are personally overseen by Dr. Jenn, ensuring safe dosing, careful monitoring, and a deeply supportive environment designed to promote healing and emotional restoration.

Ketamine works differently from traditional antidepressants, triggering powerful changes in neural pathways linked to mood and emotional resilience.

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What Is IV Ketamine Therapy?

IV ketamine therapy uses a carefully controlled dose of ketamine delivered through an intravenous infusion. Unlike SSRIs or SNRIs, which regulate neurotransmitter levels, ketamine affects multiple neurotransmitters, but it's primary effect is through the glutamate system to promote rapid neuroplasticity, allowing the brain to form new connections and break out of rigid, depressive or anxious patterns.

Because the medication is infused intravenously, dosing can be adjusted with high precision, allowing our clinicians to personalize treatment for mood disorders, trauma, or chronic pain.

How Ketamine Works in the Brain

Ketamine acts primarily as an NMDA receptor antagonist, which sets off a cascade of benefits:

• Increased neuroplasticity

Ketamine stimulates synaptic growth, improving the brain’s ability to adapt and heal.

• Rapid symptom relief

Many patients feel improvement within hours to days, even after years of trying other treatments without success.

• Reduced rumination and negative loops

By modulating glutamate pathways, ketamine can interrupt entrenched cycles of depressive, anxious, or intrusive thoughts.

• Enhanced access to emotional insight

Patients often gain clarity, perspective, or a sense of relief that complements psychotherapy and integration work.

• Pain modulation

Ketamine’s effect on the central nervous system can reduce pain sensitization and help treat chronic pain conditions.

Conditions IV Ketamine Can Help Treat

Mood & Psychiatric Conditions

  • Depression
  • Treatment-Resistant Depression (TRD)
  • Anxiety Disorders
  • Post-Traumatic Stress Disorder (PTSD)
  • Obsessive-Compulsive Disorder (OCD)
  • Suicidal Ideation
  • Addiction / Substance Use Disorders (emerging evidence)
  • Other Mood Disorders (call for more info)

Chronic Pain Conditions

  • Complex Regional Pain Syndrome (CRPS)
  • Fibromyalgia
  • Neuropathic pain
  • Migraines
  • Central sensitization syndromes

Not every patient is a fit for ketamine, so all treatment plans begin with a free medical and psychiatric screening.

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Why IV Ketamine Instead of Other Forms?

While ketamine can be administered orally, intranasally, or intramuscularly, IV infusion remains the gold standard for medical and psychiatric use because:

  • Dosing and onset are precise and predictable
  • Effects can be controlled and adjusted in real time
  • Absorption is consistent
  • Treatment can be tailored for different conditions (mood vs. pain)
  • The infusion environment is deeply supportive and therapeutically aligned

Golden Afternoon uses a trauma-informed, comfort-focused model to make the experience feel safe, warm, and healing.

Because the medication is infused intravenously, dosing can be adjusted with high precision, allowing clinicians to personalize treatment for mood disorders, trauma, or chronic pain.

Why Patients Choose Golden Afternoon Clinic

Physician-led treatment

The IV infusion process is overseen by Dr. Jenn, ensuring the highest standard of care.

Comfort-focused environment

Zero-gravity chairs, cozy blankets, aromatherapy, optional eye coverings, and curated music help create a deeply calming space for healing.

Therapeutic support

Optional integration, written reflections, and post-session grounding help patients make meaning from their experience.

Westside convenience

Accessible to Santa Monica, Venice, Mar Vista, Brentwood, Culver City, and the greater Los Angeles area.

Collaboration with therapists and psychiatrists

We coordinate with providers to ensure continuity of care and long-term success.

Learn More about the Golden Afternoon Experience